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Endocannabinoid System Overview

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The endocannabinoid system got its name in the late 1980s when researchers studying cannabis discovered the complex cell-signaling system inside the body. To better understand that cell-signaling, it’s helpful to understand homeostasis. Homeostasis is essentially your body’s efforts to keep its internal processes in balance regardless of what’s going on around you. There is some scientific research to support the idea that some people have a clinical endocannabinoid deficiency. This is a condition where your body produces fewer endocannabinoids than necessary.

Instead these indirect actions toward the receptors activate the TRPV1 receptors. These receptors are responsible for regulating body temperature, giving an individual the perception of discomfort and swelling. These are not the only functions that the endocannabinoid system plays a role in. Anytime an individual engages in voluntary physical exercise, the endocannabinoid system goes to work. The system helps in release of euphoria, while having a controlling element of our locomotor activity.

  • When phytocannabinoids are introduced into the human body, they appear to go to work in remarkable ways to keep our bodies in a state of optimum health.
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  • Dustin Sulak, a DO in Maine and Massachusetts, has written a beneficial article that has more in-depth information to help you learn about the vital role of the endocannabinoid system.
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It even has an impact on your motivational salience for rewards, which is our internal meter in our body that decides how much energy and sacrifice you are willing to put into a goal you are trying to achieve. Sativa is another subspecies of the cannabis plant that likely originated around Nepal.

Sativa strains are generally considered to have more cerebral, uplifting, and energizing effects and users often prefer Sativa dominant strains for creative work and physical activities. Cannabinoid Receptors — Found on the surface of cells, these receptors monitor and communicate information about conditions outside the cell to the inside of the cell.

So far, research has suggested that this deficiency could be what causes fibromyalgia, irritable bowel syndrome, migraines, and more. However, more research is needed before we can be sure that this is a thing. In other words, the endocannabinoid system affects a lot of your body’s functions.

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The interactions of CBD with the CB2 receptors primarily work to promote skin health, support joint health, alleviate discomforts and aid in overall functioning. CBD stimulates the endocannabinoid system, which therefore promotes homeostasis in the body, decreases swelling and helps to reduce discomforts. The interaction of CBD and the endocannabinoid system also enhances clarity and focus, decreases anxious feelings, promotes a sense of calmness, aids in recovery and assists in a better night’s rest. One would think that the interaction is direct, while it is an indirect interaction. It acts upon the CB1 and CB2 receptors, but does not bind with these receptors directly.

While you’re going about your day, your endocannabinoid system is working with the rest of your body to make sure everything is functioning as it should CBD medical. When that healthy balance is thrown off – by illness or trauma, for example – the endocannabinoid system tries to get homeostasis back. The endocannabinoid system is important because it helps maintain homeostasis – a stable internal environment within your body, where everything is running smoothly. In other words, it ensures that your body has a healthy balance of everything it needs to have. The enzymes ensure that after using endocannabinoids they are cleaned out.